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Tubbs Cooley awarded R01 from NIH/NICHD for study on NICU nursing care enhancement

Thu, 28th May, 2020

New five-year, $2.8 million grant to study nurses’ workload in relation to NICU patient safety

COLUMBUS, Ohio – Heather Tubbs Cooley, PhD, RN, FAAN at The Ohio State University College of Nursing’s Martha S. Pitzer Center for Women, Children and Youth is the Principal Investigator (PI) for a $2.8 million R01 grant funded by the National Institutes of Health (NIH)/National Institute of Child Health and Human Development (NICHD).

This R01 will fund the study, “Enhancing Nursing Care Reliability in Neonatal Intensive Care Units.” Co-investigators include the College of Nursing’s Rita Pickler, PhD, RN, FAAN; Thomas Bartman, MD, PhD, from Nationwide Children’s Hospital and other co-investigators from Cincinnati Children’s Hospital Medical Center, Johns Hopkins University, and University of North Carolina at Chapel Hill.

Tubbs Cooley and her team discovered that NICU nurses regularly miss essential care linked to neonatal safety outcomes due to their everyday workloads. With this grant, the team will now replicate this work in a larger and more heterogeneous sample of units, nurses and patients to assess strategies for workload monitoring in this patient population.

“Beyond staffing ratios and infant acuity measures, subjective workload showed the strongest correlation to care reliability,” said Tubbs Cooley. “The goal of our study is to monitor nurse workload and broaden our current understanding of its effects on care reliability.”

The team will enroll up to 210 nurses in five NICUs to report on workload and care reliability for nearly 820 infants over 1,120 shifts.

They will evaluate differential effects of objective and subjective nurse workload on care reliability in NICUs and examine relationships between shift-level factors and nurses’ subjective workload ratings. The validity of aggregating nurses’ subjective workload ratings within a shift to inform real-time measurement strategies will also be evaluated.

Tubbs Cooley and her team hope their research will lead to a better understanding of NICU nurse workloads. If they are successful, they will leverage the knowledge to improve the safety and care of NICU patients by advancing workload measurement, monitoring and intervention.

Originally posted on The Ohio State University’s College of Nursing website on May 14, 2020.

Category : General

REACH Alumna Katrina Cornish Elected to AIMBE College of Fellows

Wed, 27th May, 2020

Katrina Cornish, Ph.D., FNAI, FAAAS, REACH for Commercialization™ alumna and Professor in the College of Food, Agricultural, and Environmental Sciences was elected to The American Institute for Medical and Biological Engineering (AIMBE) College of Fellows in recognition of her distinguished and continuing achievements in medical and biological engineering.

The AIMBE announced the 2020 class of fellows in March. More information on AIMBE Fellows and the complete list of 2020 inductees can be found in the official press release.

Category : General

REACH Alumna Renee Zhao Receives 2 NSF Awards in Spring 2020

Mon, 11th May, 2020

Originally posted on Ohio State’s Institute for Materials Research website on April 29, 2020.

Renee Zhao, an assistant professor of Mechanical and Aerospace Engineering, has received  two awards from the National Science Foundation (NSF) in Spring 2020.

Earlier this year, Zhao received a five-year, $562,511 NSF Faculty Early Career Development (CAREER) Award for her research in the mechanics of soft intelligent materials.

More recently, NSF announced she will be awarded $398,773 over three years for the project “Micromechanics of Interactions Between Hard Magnetic Particles and Soft Matrix on Magneto-Mechanical Actuation.”

“The two grants will facilitate the investigation of the mechanical behavior of the magnetic soft materials,” Zhao said. “These materials are composites with hard-magnetic particles embedded in soft matrixes. Upon the application of an external magnetic field, the composite could provide untethered, fast and reversible deformation with large shape changes. The magnetic soft materials have already demonstrated potentials in designing morphing structures and actuators for various engineering applications.

“These two grants will bridge fundamental mechanics with multifunctional material design, which will further advance the magnetic soft materials’ applications in the next-generation soft robotics and biomedical devices.”

Zhao joined The Ohio State University in 2018 through the Materials and Manufacturing for Sustainability Discovery Theme, operated by the Institute for Materials Research. She is the director of the Soft Intelligent Materials Laboratory.

The NSF CAREER award is NSF’s most prestigious award in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of both, according to the agency’s website.

Zhao’s project, “Multiphysics Mechanics of Magnetic Shape Memory Polymers,” seeks to create a wide understanding of the materials, a model to demonstrate the magneto-thermo-viscoelastic behavior, as well as a simulation platform to increase interest in possible uses. The NSF Career Award will support the fundamental mechanics study of this novel soft intelligent material, the magnetic shape memory polymers, which was recently developed and published as a cover article in Advanced Materials.

In June, Zhao will begin her three-year project, studying the micromechanics of the magneto-mechanical actuation of hard-magnetic soft active materials.

Hard-magnetic soft active materials are composites with hard-magnetic particles embedded in soft matrices that can be rapidly and remotely activated. Zhao’s work will study how behavior at the microscopic level drives the operation of the macroscopic material.

Additionally, this project will promote STEM education, with a focus on  K-12 education and students from underrepresented groups, through demonstrations of hard-magnetic soft active materials utilized in soft robots.

Both awards are funded by the NSF Mechanics of Materials and Structures program.

Zhao earned a bachelor’s degree in mechanical engineering from Xi’an Jiaotong University in 2012. She then studied at Brown University, earning a master’s degree in mechanical engineering in 2014, and then a doctoral degree from the Brown School of Engineering in 2016. She was a postdoc at the MIT School of Engineering from 2016 to 2018.

Story by Mike Huson, IMR Public Relations

Contact: huson.4@osu.edu

Follow: @OhioStateIMR | @IITB_OSU_FC

Category : General

REACH for Commercialization™ Highlighted in Webinar

Thu, 30th April, 2020

The Intellectual Property Owners Association (IPO) hosted a webinar on April 28th that highlighted Ohio State ADVANCE’s REACH for Commercialization™ in their Gender Diversity in Innovation Toolkit Virtual Roadshow.

According to the IPO, diversity in innovation is crucial to a corporation or university’s long-term success. The causes for and ways to achieve diversity in innovation are many and vary by region, organization, and other factors. A panel of experts discussed the USPTO’s Progress and Potential Report and gender diversity statistics, the USPTO’s new diversity in innovation toolkit, IPO’s Gender Diversity in Innovation Toolkit, and the AUTM University and Tech Transfer Toolkit. Speakers examined these various perspectives and discussed how these tools can be used to positively impact the diversity in innovation culture within organizations.

Karen Maples, Founder & Chief Catalyst for FutureForward, cited REACH for Commercialization™ during her presentation, noting that in the past ten years, REACH participants are associated with 307 patents filed, 96 patents issued, 53 license agreements, 44 patents published and 9 startups created.


Category : General

Office of Research backs new scientific study into COVID-19 pandemic

Thu, 16th April, 2020

Originally posted by Ohio State News on April 15, 2020.

The Ohio State University has launched a funding program for a series of research projects to rapidly address critical health and community problems associated with the COVID-19 pandemic.

Six projects have been awarded a total of $263,718 of COVID-19 Seed Funding from the Office of Research. The projects involve research teams from colleges and departments across the university and are expected to be the first round of ongoing research into the pandemic.

Richard Gumina, associate professor of internal medicine, is the lead principal investigator for one of the projects. The study will obtain blood samples from SARS-C0V-2 positive patients with and without cardiovascular manifestations of COVID-19. About 100 patients will have their blood analyzed for markers to understand why some people have cardiac involvement while others do not.

“We hope we can detect changes in either cell profiling or epigenetics that might play a role in identifying those who are at risk for cardiac involvement, and develop testing to identify those patients early,” Gumina said. “And then also to be able to understand the pathology that occurs during infection so that we might develop novel therapeutic approaches to treat patients before they get too sick.”

The seed funding is not only targeting research into the virus itself, but also social science investigations that examine everything from crisis communications during the pandemic to the impact on workers at all levels of the U.S. economy.

“Ohio State, with its multidisciplinary approach, is uniquely positioned to provide innovative solutions to combat the impacts of this global pandemic, and we want to do everything possible to support our outstanding researchers in these efforts,” said Morley O. Stone, senior vice president for research. “With these seed grants, we will quickly advance our understanding of COVID-19 and its impacts to help us better address the pandemic we’re facing around the world.”

Gumina said the research funding and a fast-tracked application and approval process is critical as the novel coronavirus continues to spread. He credits the Office of Research for acting swiftly and laying the groundwork for future scientific discovery.

“It’s such a time-sensitive issue. The usual mechanisms that we would normally go through for funding for these types of ideas are just too slow to be able to meet the needs here,” he said. “I think the foresight to provide this seed funding will enable us to secure these needed samples for discovery research. Once the samples are obtained, there will be many more studies that will benefit down the road.”

In addition to the project Gumina is helping to develop, the Office of Research supported the following projects:

  • Michael Neblo, director of the university’s Institute for Democratic Engagement and Accountability (IDEA), will examine ways to improve health behaviors by developing guidelines to support communication between elected officials and the public during the COVID-19 crisis.
  • Dmitri Kudryashov, associate professor in the Department of Chemistry and Biochemistry, and his team will study the role of defensins, potent antibiotics made within the body that play an important role against invading microbes, and whether they can block virus entry into human cells.
  • Bridget Freisthler, associate dean of research in the College of Social Work, and Elisabeth Root, associate professor in the Department of Geography, will explore the COVID-19 crisis in the context of stress, social support concerns and any geographic factors associated with punitive parenting practices, including physical punishment.
  • Irina Artsimovitch, professor in the Department of Microbiology, and her study team will analyze the molecular mechanism of RNA synthesis of the novel coronavirus, increasing understanding of the building blocks of COVID-19 disease to help scientists design drug targets and vaccines.
  • Bruce Weinberg, professor in the Department of Economics, and a team of researchers will estimate the economic effects of COVID‐19 and the policy responses to it. The research will examine how those policy responses affect different types of workers.
Chris Booker
Ohio State News
Category : General

CCTS Startup Inventor Showcase Features REACH for Commercialization™ Alumna and Program

Thu, 5th March, 2020

The Optimizing Innovation, Commercialization and Entrepreneurship of Biomedical Research program of the CCTS in partnership with the Corporate Engagement Office and Nationwide Children’s Hospital’s Office of Technology Commercialization launched a new speaker series on January 13th 2020. The series features one inventor and one key resource from the innovation ecosystem each month. Inventors share stories of their successes, failures, struggles and rewards from building a startup.

The ongoing Monthly Speaker Series promotes an entrepreneurial mindset among clinicians, faculty, senior leaders, students and staff of The Ohio State University and Nationwide Children’s Hospital. Since academic entrepreneurship is a team sport, the series will also provide a forum for networking with biomedical researchers and clinicians, various players in the life science startup ecosystem, startup executives, investors and other members from the entrepreneurial community at large.

A light breakfast will be provided and networking will begin at 7 a.m. and programming will begin at 7:30 a.m. There will be time for Q&A and networking following the speakers.

The event is free but registration is required. At the leader hosted sites, a light breakfast and coffee will be provided to registered attendees which is why the deadline for RSVPs and registration is Friday, March 13th. However, registration will be open until Sunday, March 15th.

If this is your very first time, please note that we will be collecting data for tracking and reporting program metrics to the NIH, our sponsor, ONLY in your first registration form.

March Inventor: Melissa Bailey, OD, PhD
Theme: Vision for the Future
Featured resource of the month: REACH for Commercialization™

March 16, 2020
7:30 AM – 9:00 AM
James L035 Auditorium
Arthur G. James Cancer Hospital
460 W 10th Ave, Columbus, OH 43210
Registration is free but required. Register here!

Category : General

Grottoli receives Fulbright Award

Wed, 4th March, 2020

Andrea Grottoli, professor of earth sciences in the College of Arts and Sciences, has been awarded a prestigious 2020 – 2021 U.S. Fulbright Award to France.

Grottoli will visit Laboratoire Océanographique de Villefranche de Sorbonne Université to conduct research on how Mediterranean corals cope with ocean acidification during October 1, 2020 – March 31, 2021.

The research Grottoli will be conducting is in collaboration with the team of Jean-Pierre Gattuso at Sarbonne University’s Oceanographic Laboratory in Villfrance-Sur-Mer and will be a study on Mediterranean corals to determine how they are able to persist in stressful environments and how their survival can be enhanced through this century.

“Coral communities of the Mediterranean are critical ecosystems that support marine life and are essential to healthy ecosystem function,” Grottoli said. “The results of this study would be critical to identifying a mechanism for how Mediterranean corals cope with ocean acidification and could provide a possible strategy to enhance coral growth on restored or protected reefs by supplying them with zooplankton.”

During her time in France, Grottoli will also interact with researchers at the University of Perpignan and the University of Cote d’ Azur, improve her French language skills, interact with graduate students and forge new and lasting collaborations with French scientists.

For more information about the Fulbright Scholar Program, contact Joanna Kukielka-Blaser or visit fulbright.osu.edu.

Category : General

REACH Participants Highlight Their Research

Tue, 25th February, 2020

Click on the below links to hear about the exciting research being done by past and current REACH for Commercialization™ participants.

REACH 2015
Katrina Cornish, PhD
Professor, College of Food, Agricultural, and Environmental Sciences

REACH 2017
Katelyn Swindle-Reilly, PhD
Assistant Professor, College of Engineering

REACH 2020
Karen Dannemiller, PhD
Assistant Professor, College of Engineering and College of Public Health

Category : General

Participate in Upcoming Webinars on NSF Funding for Startups and Small Businesses

Fri, 21st February, 2020

Did you know that the National Science Foundation (NSF) offers funding to help turn discoveries into products or services?

Join an upcoming webinar if you are interested in translating your technology, testing if it has market potential or just learning about NSF funding opportunities.

In each webinar, a Small Business Innovation Research (SBIR) program director will discuss one of the many specific scientific topics funded through the NSF Division of Industrial Innovation and Partnerships.

Look for future webinars and read more about the full range of technology topics at America’s Seed Fund powered by NSF.

Biomedical and Digital Health Technologies
Monday, March 2, 2020
2:00-3:00 p.m. ET
Focus on translation of innovative biomedical and digital health technologies. The topic supports the early-stage development of novel medical devices and wearables, components, processes, systems, algorithms, networks, applications, or services that target improvement in health.

Distributed Ledger Technologies
Thursday, March 5, 2020
2:00-3:00 p.m. ET
Focus on translation of innovation on technologies spanning all areas of distributed ledger including, but not limited to, blockchains, Directed Acyclic Graphs (DAGs), and related capabilities (cryptography, smart contracts, etc.).

Artificial Intelligence
Monday, March 9, 2020
2:00-3:00 p.m. ET
Focuses on translation of leading-edge innovation in all areas of artificial intelligence (AI) — including, for example, machine learning, computer vision and natural language processing — and applications of such innovations in areas of commercial and societal impact, such as industries of the future and education.

Pharmaceutical Technologies
Thursday, March 12, 2020
2:00-3:00 p.m. ET
Focus on the translation of a wide range of innovative technological areas to advance the discovery, early-stage development and characterization, formulation, delivery, and/or manufacture of novel drugs, moieties, compounds, products, processes, platforms or services that will improve the selection, quality, or price of pharmaceutical therapies.

Biological Technologies
Monday, March 16, 2020
2:00-3:00 p.m. ET
Focus on the translation of a wide range of technological areas to advance engineering and science innovation across the biological spectrum. Biological technologies have disrupted decades-old chemical, agricultural, and medical products and services, producing a new bioeconomy.

Thursday, March 19, 2020
2:00-3:00 p.m. ET
Focuses on the translation of technology to advance cybersecurity, security and authentication to address issues in an increasingly networked, distributed, and asynchronous world. Cybersecurity involves hardware, software, networks, data, people and integration with the physical world.

SBIR, email: sbir@nsf.gov

NSF Related Organizations
Directorate for Engineering
Industrial Innovation and Partnerships

Related Programs
Innovation Corps – National Innovation Network Teams Program (I-CorpsTM Teams)
Partnerships for Innovation
Small Business Innovation Research Program Phase I
Small Business Technology Transfer Program Phase I

Category : General

REACH 2019 Alumna Wins NSF CAREER Award

Thu, 6th February, 2020

Originally posted on mse.osu.edu.

photo of Professor Jenifer Locke Ohio State

The Department of Materials Science and Engineering congratulates Jenifer Locke, Assistant Professor of Materials Science, for winning the coveted NSF CAREER award, one of the biggest awards given to a young faculty member by the National Science Foundation.

The research

Professor Locke will be researching how the environment causes cracking and failure to be accelerated in aluminum-based alloys. Aluminum-based alloys are known to have a variable resistance to environment-assisted cracking that depends upon other elements present in the alloy. The award will drive research and education on why certain aluminum-based alloys are more resistant to the environment-induced degradation than others, which can inform more sustainable use of these and other metals and prevent failure.

Dr. Locke explains, “Essentially we will be working to test a hypothesis that certain alloys’ metallurgically controlled corrosion behavior (which is typically seen as bad) facilitates less aggressive crack tip conditions, allowing them to be inherently more resistant to environment-assisted cracking.”

To test this hypothesis, Locke will be performing environment-assisted cracking experiments (experiments that involve corrosion and mechanical stressing at the same time) on model alloys that span the range of more resistant to less resistant based on the hypothesis. During these experiments, Locke will use an experimental technique developed in her lab lab under previous NSF funding to monitor the crack tip pH and correlate it to the resistance of each alloy type.

The NSF CAREER funding will support a graduate student for five years, five years of REU (Research Experience of Undergraduates), and RET (Research Experience for Teachers) participants. The combined team will work on research to develop corrosion-related demos, which will be accompanied by custom-made videos to teach the community about corrosion and its relation to sustainability.

The results

Her research will be used to improve the performance and long-term sustainable use of metals. Professor Locke cites the research as a function for learning why some alloys are inherently better and foresees the creation of new, more resilient materials.

Beginner’s Locke?

A young faculty member can win a NSF CAREER award one time and has three chances to apply. This was Professor Locke’s first time applying for the award. Call it beginner’s luck or an opportunity to better understand the behaviors of alloys at the hands of a faculty member expertly versed in corrosion; it’s a win for materials science, the environment, and Ohio State.

Ohio State continues to justify its rank as a world leader in corrosion-related research, which is hosted in the department’s Fontana Corrosion Center. We are known around the world for leading research in this area thanks to faculty members like Jerry FrankelRudy Buchhiet and their predecessors. This NSF CAREER award illustrates that the young faculty in the Fontana Corrosion Center and Department of Materials Science and Engineering are maintaining this high quality of fundamental research.

On what the NSF CAREER award means to me and my career

“This is one of the biggest awards a young faculty member can achieve, and it is so affirming. Sometimes being a tenure-track professor, spouse, and mom can beat you down…as all working moms know. When working on this proposal, my son and I both got sick. I thought about scrapping it and trying again next year. I pushed through, woke up at 5AM during a family vacation to work on my proposal so I would not miss a moment of quality time with my kids, and I WON the award! This win affirms that all the hard days were worth it and that I can be a successful researcher, teacher, and mom simultaneously.”

Giving back. Paying forward.

Another rewarding aspect to Locke’s NSF CAREER award is that it allows her to give back to her undergraduate institution, Wittenberg University. Through the RET program, she is partnering with the Physics Department at Wittenberg, where Jenifer got her academic start, and Professor Elizabeth George to sponsor an undergraduate student from Wittenberg University in her lab every year. Many physics students at Wittenberg University, including Professor Locke and her spouse, want to become engineers but do not necessarily have the ability to work in a large engineering research lab. This partnership will allow someone like Jenifer, or someone who wants to go into education only, to engage in large academic engineering research.

I’m really excited to start this partnership with Wittenberg University! – Professor Jennifer Locke, PhD

At Ohio State

photo of Jenifer Locke Ohio State ProfessorProfessor Jenifer Locke loves the opportunity to engage in learning every day at Ohio State, “I get to teach. I get to learn through research. I get to learn from discussions with other faculty and researchers in my field, and I get to help others learn more about themselves and their passions!”

Faculty like Professor Jenifer Locke embody the spirit of Ohio State University and support the mission of the college. She enriches the lives of students through her lessons in the classroom and by personal example, and the research she and her team will yield complement the focus of the college.

Category : General